Cost of western blot test in india11/22/2023 While the initial IgG test looks for a single antibody protein to distinguish and identify HSV-1 and HSV-2, the WB looks for all of the proteins associated with herpes antibody. The UW Western Blot is widely considered the gold standard for herpes antibody testing. The WB test is not FDA-approved, needs to be ordered directly from UW, and a blood sample sent directly to their academic lab for processing. To access confirmatory testing and confirm a herpes diagnosis – patients will need to order the Western Blot (WB) from the University of Washington. This two-step process has been recommended per the CDC guidelines because currently available diagnostic IgG antibody tests are so often false negative/positive.Īvailability of the confirmatory test (the second step test) is limited and many providers do not know how to take steps to order the confirmatory testing for patients. Meaning once the initial IgG antibody test is performed, a follow-up confirmatory test is recommended. Most often, false positive results are found in the index value range of 1.1 to 5.0 but IgG false positives can be as high as 17.Īs a result, CDC guidelines call for TWO STEP testing to confirm a herpes diagnosis. Tests can also have false negative results.
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